None
Conditions
Interventions
Local anesthesia group:15ml of 1% lidocaine +0.25% ropivacaine mixture (one vertebral body) was infiltrated layer by layer from skin to vertebral body
the sufentanil group:15ml of 1% lidocaine +0.25% ropivacaine mixture (one vertebral body) was infiltrated layer by layer from skin to vertebral body. Before peeling, sufentanil 0.1ug/kg+100ml0.9%NS wa
Hydromorphone group:15ml of 1% lidocaine +0.25% ropivacaine mixture (one vertebral body) was infiltrated layer by layer from skin to vertebral body. Before peeling, hydromorphone 0.01mg/kg+100ml0.9%NS
Sponsors
Jiangyin People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years old; 2. Body mass index (BMI) 18.5-30kg/m^2; 3. ASA I-III level; 4. Patients undergoing percutaneous spondyloplasty or percutaneous balloon expansion kyphoplasty; 5. Voluntarily participated and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Chronic pain, chronic use of analgesics, psychotropic drugs (including opioids, NSAIDs, sedatives, antidepressants), alcohol abuse; 2. A history of opioid allergy; 3. Used sedatives, analgesics, anti-pruritus drugs 24 hours before surgery, and used monoamine oxidase inhibitors or antidepressants within 15 days before surgery; 4. Patients with abnormal increase of liver and renal function (ALT, AST, BUN, Cr) before operation and liver surgery; 5. History of recovery from abnormal surgical anesthesia; 6. Patients with previous sleep apnea, esophageal reflux disease history, COPD history; 7. Patients with difficult airway intubation are expected; 8. Participated in other drug trials within three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of intraoperative body movements;postoperative pain score(VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| time of operation;awakening time;Intraoperative respiratory depression;Postoperative nausea and vomiting;The first time to get out of bed after surgery;Preoperative cognitive function;postoperative cognitive function; | — |
Countries
China
Contacts
Public ContactChen Jianqing
Jiangyin People's Hospital
Outcome results
None listed