Skip to content

Response evaluation using contrast-enhanced ultrasound for hepatocellular carcinoma treated with PD-1 antibody plus with lenvatinib therapy: A Prospective Study

Response evaluation using contrast-enhanced ultrasound for hepatocellular carcinoma treated with PD-1 antibody plus with lenvatinib therapy: A Prospective Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400094263
Enrollment
Unknown
Registered
2024-12-19
Start date
2024-03-15
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

Non response group:None

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age greater than 18 years old; (2) The patient was diagnosed with hepatocellular carcinoma and was treated with PD-1 antibody combined with lenvatinib; (3) Routine ultrasound and contrast-enhanced ultrasound examination within one week before receiving treatment; (4) Conventional ultrasound, contrast-enhanced ultrasound, enhanced magnetic resonance or computed tomography after combination therapy.

Exclusion criteria

Exclusion criteria: (1) The patient receives local treatment before or during treatment; (2) Pregnant and lactating women; (3) The patient is allergic to eggs, milk, seafood, and contrast media, and cannot undergo ultrasound contrast examination; (4) Previous diagnosis of malignant tumors other than hepatocellular carcinoma; (5) Incomplete clinical data or ultrasound examination; (6) History of liver surgery.

Design outcomes

Primary

MeasureTime frame
Residual viable tumor;

Countries

China

Contacts

Public ContactLuo Yukun

Chinese PLA General Hospital

lyk301@163.com+86 133 1137 3556

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026