Ametropia
Conditions
Interventions
SMILE Xtra group:Corneal accelerated cross-linking
Conventional SMILE group:None
Sponsors
Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: SMILE group: (1) age >=18 years old; (2) spherical lens degrees -1.00 D- -10.00 D, and columnar lens degrees -5.00 D and below (in accordance with the "Expert Consensus on the Specification of China's Femtosecond Laser Small-Incision Corneal Stromal Lens Removal Surgery 2018"); (3) good fixation in both eyes; (4) refractive stability of more than 2 years (annual refractive change within 0.50 D); (5) Cornea: clear without obvious cloudiness or opacification; normal morphology on corneal topography examination, no tendency to cone cornea; (6) more than 2 weeks of discontinuation of spherical soft lenses, more than 4 weeks of discontinuation of astigmatic soft lenses and rigid oxygen-permeable corneal contact lenses, and more than 12 weeks of discontinuation of keratoplasty lenses. SMILE Xtra group: In addition to the above conditions, (1)Corvis biomechanical index (Corvis biomechanical index (CBI)) > 0.3, corneal topography combined biomechanical index (tomographic biomechanical index (TBI)) > 0.3; (2) expected postoperative corneal stromal bed thickness > 300 µm; (3) corneal thinnest point thickness > 400 µm.
Exclusion criteria
Exclusion criteria: (1) patients with keratoconus and subclinical keratoconus; (2) patients with anterior segment disease, active disease and fundus disease; (3) patients with a history of ocular trauma and surgery; (4) patients with severe diabetes, systemic connective tissue diseases or autoimmune diseases; (5) pregnant and lactating women; (6) patients with anxiety, depression and other serious psychological and mental diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual acuity(VA);Dioptric;Corneal biomechanical index;Corneal curvature;Corneal thickness;Cornea densito;Intraocular pressure; | — |
Countries
China
Contacts
Public ContactJi Peng
Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed