Bladder Cancer
Conditions
Interventions
BCG Morning Group:Morning intravesical BCG instillation
BCG Afternoon Group:Afternoon intravesical BCG instillation
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Individuals aged 18 years or older with full civil capacity, who fully understood the study and signed the informed consent; (2) Patients with urothelial carcinoma (without squamous cell or multiple cell type differentiation) initially confirmed by histology or cytology; (3) Patients who required BCG intravesical (induction + maintenance) instillation after transurethral resection of bladder tumor (TURBT); (4) ECOG performance status score of 0-1; (5) TNM stage: Ta/T1N0M0.
Exclusion criteria
Exclusion criteria: (1) Patients with other malignant tumors; (2) Failure of early BCG infusion; (3) Patients with serious underlying diseases or complications; (4) Patients who have received special immunotherapy and have been assessed to be immunocompromised or immunodeficient; (5) Patients who are pregnant or breastfeeding; (6) Patients with serious abnormalities in clinical laboratory tests (such as liver and kidney function, blood gas analysis); (7) Patients with serious mental health problems.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor recurrence rate;Relapse free survival, RFS;Progression free survival, PFS;Overall survival, OS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Laboratory examinations; | — |
Countries
China
Contacts
Public ContactHan Ping
Department of Urology/Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Outcome results
None listed