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Clinical research on the treatment of temporomandibular joint osteoarthritis with platelet concentrate CGFs

Clinical research on the treatment of temporomandibular joint osteoarthritis with platelet concentrate CGFs

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094244
Enrollment
Unknown
Registered
2024-12-19
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporomandibular joint osteoarthritis,TMJOA

Interventions

Injection medication group:Local injection of CGFs for the treatment of TMJOA
Surgical treatment group:Open surgery for the treatment of TMJOA

Sponsors

The Affiliated Stomatological Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Autoimmune diseases involving the temporomandibular joint, acute capsulitis, benign or malignant temporomandibular joint lesions, myofascial pain, and functional disorders.

Exclusion criteria

Exclusion criteria: 1. Patients with severe perforation and deformation of the joint disc, unable to establish stable occlusion in the entire mouth; 2. Patients with radiation-induced osteomyelitis, acute or chronic osteomyelitis, or severe osteoporosis; 3. Patients with acute or chronic infections in the TMJ area, a history of trauma, rheumatoid arthritis, or other autoimmune diseases, and any other history of diseases that may affect jawbone growth and development; 4. Patients who have previously undergone temporomandibular joint surgery; 5. Patients with a follow-up period of less than 12 months.

Design outcomes

Primary

MeasureTime frame
Pain relief and improvement of joint function;Disc-condyle relationship;Joint space;Condylar volume and surface area;Temporomandibular Joint Functional Score;

Countries

China

Contacts

Public ContactPing Zhang

The Affiliated Stomatological Hospital of Nanjing Medical University

zpnjmu@163.com+86 159 5187 1313

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026