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Mechanism of intestinal barrier injury in the occurrence and development of sepsis

Mechanism of intestinal barrier injury in the occurrence and development of sepsis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400094241
Enrollment
Unknown
Registered
2024-12-19
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

sepsis group:NA
healthy group:NA

Sponsors

Wuxi people’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Sepsis group: Patients with sepsis admitted to the Department of critical care medicine of Wuxi People's Hospital; Health Group: healthy people who received physical examination in the physical examination center of Wuxi People's hospital; 2.Over 18 years old.

Exclusion criteria

Exclusion criteria: 1.Receiving immunosuppressive therapy (eg, immunosuppressants, high-dose glucocorticoids, chemotherapy, and radiotherapy); 2.Had diseases with impaired immunity (eg, carcinoma, leukemia, lymphoma, and AIDS); 3.Had intestinal diseases (eg, inflammatory bowel disease, intestinal obstruction, and mesenteric vascular obstruction); 4.Had gastrointestinal surgery history within a year; 5.Pregnancy status or perinatal period.

Design outcomes

Primary

MeasureTime frame
28-day death;—

Countries

China

Contacts

Public ContactWang Yifeng

Wuxi people’s Hospital

wangyifeng@njmu.edu.cn+86 15995229306

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026