Cardiac surgery associated acute kidney injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age = 7 years; (2) Elective cardiac surgery under CPB; (3) ASA class I-IV.
Exclusion criteria
Exclusion criteria: (1) Combined severe renal insufficiency (preoperative dialysis or preoperative creatinine value >3 mg/dL); (2) Emergency surgery; (3) Secondary cardiac surgery; (4) Preoperative use of nephrotoxic drugs; (5) Active infection (e.g., sepsis); (6) Preoperative need for extracorporeal life support; (7) Anticipated CPB minimum temperature <32°C (e.g., heart transplant, aortic arch replacement surgery); (8) Incomplete clinical data to complete statistical analysis; (9) Concurrent participation in other clinical studies that conflict with this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative CSA-AKI; | — |
Secondary
| Measure | Time frame |
|---|---|
| ICU length of stay;Postoperative awakening time;Duration of postoperative mechanical ventilation;Length of hospitalization;Hospital fees;All-cause mortality 30 days after surgery;Incidence of vital organ complications within 30 days of surgery; | — |
Countries
China
Contacts
West China hospital, Sichuan University