primary open angle glaucoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for TON, POAG, RP, or AMD; 2. Aged 18-70 years; 3. The best corrected visual acuity of at least one eye is greater than or equal to 35 letters (20/200 on the Snellen chart), and the visual field radius of at least one eye is greater than 5°; 4. Agree to participate in this research and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) People with other eye diseases such as corneal, iris, and visible lens pathology and various fundus pathologies in the study eye, such as keratitis, uveitis, glaucomatous ciliary body inflammation syndrome, retinal detachment, retinal arteriovenous occlusion, and diabetic retinopathy, etc.; (2) People with severe dry eye; (3) People with significant clouding of the refractive interstitium, which, in the judgment of the investigator, affects visual acuity, visual field and other examinations; (4) People with one eye or ocular deformity; (5) People with any active or recurrent intraocular infection or intraocular inflammation in any eye within the last 3 months; (6)People with any internal eye surgery within the last 6 months in the study eye; (7) People with ocular trauma within the last 6 months in the study eye; (8) Those who need to use circulatory and neurotrophic drugs that cannot be discontinued for a short period of time; (9) Anyone who is planning to undergo any eye surgery or laser treatment; (10) People with intellectual or cognitive impairment or mental illness can not give full informed consent (except for patients with mild anxiety or depression); (11) Those who are participating in a clinical trial of another drug, or have participated in a clinical trial of a similar drug within 3 months; (12) People with a positive pregnancy test, pregnant or lactating women, or those planning a pregnancy; (13) Those who, in the opinion of the investigator, are not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vision field;optical coherence tomography angiography; | — |
Secondary
| Measure | Time frame |
|---|---|
| best corrected vision;pattern visual evoked potential;25-Item National Eye Institute Visual Function Questionnaire;electroretinogram; | — |
Countries
China
Contacts
Eye Hospital, China Academy of Chinese Medical Sciences