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Comparison of different ventilation modes in laparoscopic surgery in Trendelenburg position

Comparison of different ventilation modes in laparoscopic surgery in Trendelenburg position

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094228
Enrollment
Unknown
Registered
2024-12-19
Start date
2024-12-20
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary complications

Interventions

Volume-controlled ventilation group:Volume-controlled ventilation mode
Pressure controlled ventilation group:Pressure-controlled ventilation mode

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1)Age greater than 60 and less than 80 years old (2)ASA classification I-III (3)Elective laparoscopic surgery patients in Trendelenburg position (4)BMI<28 kg/m2 (5)Patients with normal preoperative arterial oxygenation, and partial pressure of carbon dioxide (6)The duration of the operation is more than 2 hours (7)Signed informed consent form

Exclusion criteria

Exclusion criteria: (1) emergency surgery, unplanned reoperation (2) contraindication of arterial catheterization (3) Severe heart, lung, liver and renal insufficiency (4) Preoperative complicated with obvious respiratory diseases, such as serious pulmonary infection, etc (5) Preoperative SpO2 = 90% or PaO2 = 60mmHg when breathing air, preoperative hemoglobin < 90g / L (6) It is expected that there is a difficult airway

Design outcomes

Primary

MeasureTime frame
Pulmonary complication rate at 3 days postoperatively;

Secondary

MeasureTime frame
Ppeak;Pplat;PaO2;PaCO2;Oxygenation index;Heart rate;Blood pressure;Cdyn;VD/VT;AaDO2;

Countries

China

Contacts

Public ContactWang Bin

The First Affiliated Hospital of Chongqing Medical University

774935778@qq.com+86 136 3781 5096

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026