postoperative delirium
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged between 65 and 85 ; (2) Patients who undergoing tracheal intubation and down-laparoscopic radical treatment of gastrointestinal malignant tumors; (3) The estimated operation time is =2 hours, and the postoperative hospitalization time is at least 2 days; (4) American Society of Anesthesiologists (ASA) level II or III, no obvious surgical contraindications; (5) Good liver and kidney function; (6) The patient participates voluntarily and signs an informed consent form
Exclusion criteria
Exclusion criteria: (1) Participating in other clinical trials in the past 3 months; (2) Have a history of dementia, mental illness or other central nervous system diseases; (3) Preoperative sleep disorder [Pittsburgh sleep quality index (PSQI) score] =6 points; (4) Preoperative simple mental state examination (Mini-Mental State Examination, MMSE) score 200/110mmHg); (11) Hepatic and renal insufficiency (Child C); (12) ASA IV or V level
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of patients experiencing postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh sleep quality index;postoperative pain;C- reactive protein;Intraoperative hemodynamic indicators; | — |
Countries
China
Contacts
Guangzhou Institute of Cancer Research, the Affiliated Cancer Hospital, Guangzhou Medical University