adenomyosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with adenomyopathy (disease) first diagnosed by US and/or MRI (diagnostic criteria: myometrial cyst, distorted and uneven myometrial echo structure, abnormal myometrial echo structure lesions with blurred boundaries, spherical and/or asymmetrical uterus); 2, >=18 years old, premenopausal or strongly want to preserve fertility; 3, unbearable dysmenorrhea or abnormal uterine bleeding, excessive menstruation. 4. There was no history of medium-dose hormone pills, GnRH agonists (GnRHa), testosterone derivatives, estrogen antagonists, aromatase inhibitors, DNG, or other progesterone or surgical treatment prior to inclusion. 5. No indications for surgery.
Exclusion criteria
Exclusion criteria: 1. Electronic medical record data is incomplete. 2. Lost follow-up after implantation. 3. Try to get pregnant after implantation. 4. There are indications for surgery. 5, uterine malformations, chronic pelvic inflammatory disease, ovarian tumors, other endocrine diseases, coagulation abnormalities or active thrombotic diseases, moderate to severe anemia, cardiovascular diseases, liver and kidney dysfunction and sexual function dependent malignancies. 6. Current pregnancy and lactation period. 7. Receive hormone therapy within 3 months before starting treatment. 8. Unexplained genital bleeding (vaginal or vulva). 9. Any contraindications to LNG-IUS placement, previous adenomyosis surgery, postmenopausal status, or patient refusal to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| dysmenorrhea;menstrual blood volume;focal size; | — |
Countries
China
Contacts
Hubei Maternal and Child Health Hospital, Huazhong University of Science and Technology