Bethesda III/IV nodules
Conditions
Sponsors
The First Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged 18 to 80 years old, regardless of gender; 2.Confirmation of Bethesda III or IV by fine-needle aspiration; 3.No clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on US, neck and chest CT; 4.Refusal or ineligibility for surgery; 5.Follow-up period >12 months, patients underwent ultrasound examination all the ultrasound images before and after ablation have high quality.
Exclusion criteria
Exclusion criteria: 1.Nodules had suspicious of malignancy in US; 2.Previous radiation to the head and neck; 3.Negative results of Bref V600E, RAS, TERT test, or calcitonin and CEA level above normal value; 4.Coagulation disorder,Serious heart, respiratory, liver, or renal failure; 5.Dysfunction of the vocal cord on the opposite side;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| volume reduction rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| complications;cosmetic score;symptom score;delayed surgery;thyroid function;quality of life; | — |
Countries
China
Contacts
Public ContactYukun Luo
The First Center of Chinese PLA General Hospital
Outcome results
None listed