rosacea
Conditions
Interventions
External control group:regular therapy
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients with Rosacea diagnosed according to Rosacea Treatment Guidelines (2017 edition).Diagnosis confirmed by two senior dermatologists; history of disease longer than 1 year (2) CEA score >= 1 and/or GFSS score >= 4; (3) not taking systemic therapeutic drugs (e.g. carvedilol, paroxetine, isotretinoin, etc.) within 4 weeks prior to study entry (4) Age 18 to 65 years; (5) Patients volunteered to participate in the study and signed a written informed consent form.
Exclusion criteria
Exclusion criteria: (1) Serious systemic diseases (including cardiac and cerebrovascular diseases, thyroid diseases, liver and kidney dysfunction, etc.) (2) Other serious skin diseases (seborrheic dermatitis, systemic lupus erythematosus, dermatomyositis, etc.) (3) Serious mental disorders (e.g. schizophrenia, bipolar disorder) (4) Pregnant or breastfeeding women, or planning to have a pregnancy in the last 3 months (5) Previous transcranial magnetic therapy (6) Contraindications to magnetic resonance examination, such as metal implants in the body, claustrophobia, etc. (7) Presence of moderately severe rhinorrhea changes (8) Contraindications to TMS, e.g. epilepsy, cerebral haemorrhage, pacemaker, etc. (9) Other people who cannot cooperate with the completion of the TMS treatment operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Global flushing severity scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinican's Erythema Assessment;Patient's Self Assessment;Investigator's Global Assessment;Rosacea Area and Severity Index;Amplitude of Low Frequency Fluctuations;Reho;Functional connection;Brain network;Dermatology Life Quality Index;RosaQoL;Hospital Anxiety and Depression Scale;Pittsburgh Sleep Quality Index; | — |
Countries
China
Contacts
Public ContactXian Jiang
West China Hospital, Sichuan University
Outcome results
None listed