Coronary heart disease
Conditions
Interventions
Observation group:Intraoperative application of landiolol
Control group:None
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
30 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients undergoing CABG under non-stopping cardiac conditions; 2. Patients diagnosed with coronary atherosclerotic heart disease by the associate chief physician of cardiovascular medicine or cardiovascular surgery or above; 3. 30 years old or older; 4. Patients with transient atrial fibrillation who underwent surgery with sinus rhythm without amiodarone treatment.
Exclusion criteria
Exclusion criteria: 1. Persistent atrial fibrillation in the past; 2. Patients who received amiodarone as initial therapy for atrial fibrillation prior to initiation of beta-blocker therapy; 3. Patients with permanent pacemakers;4. Patients with severe cardiac dysfunction such as NYHA Class IV, left ventricular ejection fraction < 20%, cardiogenic shock and emergency CABG; 5. Patients with sinus bradycardia (resting heart rate < 50 beats/min, second or third degree atrioventricular block); 6. Patients with renal insufficiency who require dialysis; 7. Patients with airway diseases such as asthma or chronic obstructive pulmonary ventilation dysfunction; 8. Patients who have previously performed CABG; 9. Patients with cardiac arrest after CABG or combined with other valve operations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of new cases of atrial fibrillation after operation;1 month postoperative mortality;3 month postoperative mortality;6 month postoperative mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of postoperative stay;Duration of postoperative ventilator treatment;Duration of post-operative intensive care;Operation duration;Postoperative cardiokinase;Mean arterial pressure after surgery;Postoperative inflammatory factor;Postoperative left ventricular ejection fraction;Treatment cost; | — |
Countries
China
Contacts
Public ContactJianjun Yang
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed