None
Conditions
Interventions
Test group:The first and second weeks: soak in clean water for 5 minutes every day
The third and fourth week: soak in clean water for 5 minutes every day for the first six days, and soak in denture cleaning tablets for 5 minutes on the seventh day
The fifth and sixth weeks: soak denture cleaning tablets (polar) for 5 minutes every day
Week 7 and week 8: soak denture cleaning tablets twice a day for 5 minutes each time.
Sponsors
Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1) Age: 18-35 years old. 2) Demonstrated understanding of the research procedures, limitations, and willingness to participate, as evidenced by voluntary written informed consent, and a signed and dated copy of the informed consent was received. 3) Patients with dental deformity and treated with invisible braces. 4) Brush your teeth twice a day. 5) The teeth and periodontal tissues are basically healthy.
Exclusion criteria
Exclusion criteria: 1) Have participated in this study or other clinical studies (including cosmetic Studies) or received study drugs within 30 days after the screening visit. 2) Smokers. 3) Are taking drugs to reduce saliva flow, or have dry mouth. 4) Pregnant & lactating women. 5) Allergic to the test sample. 6) There are active caries, endodontic disease and periapical disease. 7) There are periodontal disease and oral mucosal disease. 8) Have been treated with antibiotics or glucocorticoids or bacteriostatic mouthwash. 9) Have systemic diseases. 10) Any clinically significant or relevant oral abnormalities considered by the investigator that may affect participants' participation in the study. 11) Recently (within 30 days) had gingival / oral surgery. 12) Employees of the sponsor or research institution or their immediate family members. 13) Employees of oral care product manufacturers or their immediate family members.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bacterial survival rate;Change in total number of colonies on the surface of the invisible aligner; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bacterial adhesion;Bacterial proliferation;Plaque staining; | — |
Countries
China
Contacts
Public ContactBing Fang
Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed