Ulcerative colitis
Conditions
Interventions
Sodium propionate group:Subjects took 1g sodium propionate orally daily
placebo group:Subjects took 1g of corn starch orally daily
Sponsors
The First Affiliated Hospital, College of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1: Age 18-70 years old, gender is not limited 2: Subjects with confirmed ulcerative colitis were evaluated by endoscopy, histology, and imaging 3: Subjects receiving medication 4: Patients voluntarily sign informed consent forms
Exclusion criteria
Exclusion criteria: 1: Patients with severe ulcerative colitis 2: Patients treated with systemic or rectal steroids 3: Patients known to be allergic to any investigational drug 4: Patients with liver and kidney dysfunction 5: Pregnant and lactating patients 6: Patients with a history of colorectal cancer 7: Patients with a history of total or partial colectomy 8: Subjects with disease states associated with hypoxemia, including cardiopulmonary insufficiency 9: Patients with positive fecal cultures for intestinal pathogens and positive tests for fecal eggs and parasites
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endoscopic remission combined with histological improvement; | — |
Secondary
| Measure | Time frame |
|---|---|
| erythrocyte sedimentation rate, ESR;C-reactive protein, CRP;Fecal calvetin;Fecal lactoferrin; | — |
Countries
China
Contacts
Public ContactZhe Shen
The First Affiliated Hospital, College of Medicine, Zhejiang University
Outcome results
None listed