Type 2 diabetes mellitus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1)elderly patients: aged 65 to 80 years. (2)T2DM: diagnosed according to Guideline for the Management of Diabetes Mellitus in the Elderly in China (2024 edition). (3) MAU: urinary albumin-to-creatinine ratio (UACR) between 30 and 300 mg/g, with repeated UACR measurements over 3 to 6 months, meeting the criteria in 2 out of 3 tests, excluding other interfering factors such as infections.
Exclusion criteria
Exclusion criteria: (1) Left ventricular ejection fraction (LVEF) <50% as indicated by transthoracic echocardiography. (2) Conditions affecting left ventricular function, including type 1 diabetes, clinically diagnosed heart failure, hypertension, coronary heart disease, arrhythmias, valvular heart disease, congenital heart disease, cor pulmonale, thyroid dysfunction, and hepatic or renal insufficiency. (3) Poor quality of cardiac ultrasound imaging, not meeting the requirements for image analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| global work efficiency (GWE); | — |
Secondary
| Measure | Time frame |
|---|---|
| global longitudinal strain (GLS), global work index (GWI), global constructive work (GCW), global wasted work (GWW);Routine transthoracic ultrasound indicators;physical examination index;Clinical biochemical index; | — |
Countries
China
Contacts
Sichuan Provincial People's Hospital