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A single-center, prospective, single-arm study of hydromorphone in the treatment of acute chest pain

A single-center, prospective, single-arm study of hydromorphone in the treatment of acute chest pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094047
Enrollment
Unknown
Registered
2024-12-16
Start date
2024-12-16
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Chest pain

Interventions

treatment group:Hydromorphone 1mg was given intravenously and conventional treatment was performed at the same time

Sponsors

Nanjing Drum Tower Hospital Affiliated to Medical School of Nanjing University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: (1) Age of 18-64 years old; (2) no gender limitation; (3) for patients with acute chest pain, the time from pain onset to visit was =24; (4) severe pain requiring opioid control as judged by the emergency department physician; (5) Informed consent was obtained from patients or their families.

Exclusion criteria

Exclusion criteria: (1) known allergy to hydromorphone or morphine; (2) Systolic blood pressure < 100mmHg, oxygen saturation < 95%, pulse < 60 beats/min;Use of acetaminophen or nonsteroidal anti-inflammatory drugs within the past 8 hours; (4) presence of chronic pain, defined as pain lasting more than 12 weeks; (5) delirium, alcohol withdrawal symptoms or other drug poisoning; (6) pregnant or lactating women; (7) patients with mental and neurological diseases, cognitive and consciousness disorders and unable to express correctly; (8) participating in any other research simultaneously; (9) presence of factors that increase the risk associated with study participation (life-threatening chest requiring rapid diagnostic or therapeutic intervention)Pain patients (resuscitated, excluding chest pain due to myocardial infarction) were judged by the investigator to be ineligible Select the study.

Design outcomes

Primary

MeasureTime frame
The degree of pain reduction after 30 minutes of medication;

Secondary

MeasureTime frame
Success rate of analgesia;Total dose of remedial medication;

Countries

China

Contacts

Public ContactJun Wang

Nanjing Drum Tower Hospital

wjgaogou@163.com+86 138 5183 0326

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026