Impact of Controlled Propofol Delivery via Fine-Bore Infusion Extension on the Incidence of Hypoxemia During Sedation for Gastroscopy: A Single-Center, Prospective, Randomized Controlled Trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400094042

Enrollment

Unknown

Registered

2024-12-16

Start date

2024-12-16

Completion date

Unknown

Last updated

2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sedation for gastroscopy

Interventions

Group F:The intervention group (Group F) received propofol via a fine-bore infusion extension tube (Shenzhen Shunmei Medical Co., Ltd.), characterized by an inner diameter of 2.03 mm and a length of 1

Group C:The control group (Group C) was administered propofol through a coarse-bore extension tube (Shenzhen Shunmei Medical Co., Ltd.) with an inner diameter of 3.05 mm and a length of 150 cm.

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Adults aged =18 years; 2. American Society of Anesthesiologists physical status (ASA-PS) classification of ?-?; 3. Written informed consent provided

Exclusion criteria

Exclusion criteria: 1. Severe hepatic or renal dysfunction (ASA-PS ?-?); 2. Known allergies to propofol or the study drug; 3. Pregnancy or breastfeeding; 4. A history of substance abuse; 5. The presence of chronic respiratory diseases such as chronic obstructive pulmonary disease or asthma.

Design outcomes

Primary

Measure	Time frame
Hypoxemia;	—

Secondary

Measure	Time frame
Severe hypoxemia;Time to achieve target sedation depth;Total propofol dosage;incidence of pain on propofol injection (POPI);	—

Countries

China

Contacts

Public ContactFan Xiaohua

Changhai Hospital, Naval Medical University

fxh95007@126.com+86 139 1791 3859

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026