Skip to content

A correlative study of the effects of anesthetic drugs on perioperative electroencephalogram (EEG) and functional brain imaging, as well as the prognosis of spinal cord stimulation electrode implantation in patients with impaired consciousness.

A correlative study of the effects of anesthetic drugs on perioperative electroencephalogram (EEG) and functional brain imaging, as well as the prognosis of spinal cord stimulation electrode implantation in patients with impaired consciousness.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400094039
Enrollment
Unknown
Registered
2024-12-16
Start date
2024-11-21
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disorders of consciousness

Interventions

DoC P1 group:NA
DoC P2 group:NA
DoC K group:NA
Healthy P1 group:NA
Health K Group :NA

Sponsors

peking university international hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: DoC group can be defined as follows: 1) Patients between the ages of 18 and 65 years; 2) SCS surgery; 3) Tracheotomy; 4) Patients with a diagnosis of VS or MCS (traumatic, stroke*, hypoxia and toxic/metabolic brain injury). In this context, the term "stroke" encompasses a range of conditions, including ischemic stroke, subarachnoid hemorrhage, and non-invasive cerebral hemorrhage. The intravertebral occupancy group is defined as follows: The subjects were between the ages of 18 and 65 years old, underwent vertebral occupancy resection, and remained conscious throughout the procedure.

Exclusion criteria

Exclusion criteria: The DoC group was comprised of individuals who exhibited single or multiple organ failure, as well as those who demonstrated combined severe hypertension, cardiac, pulmonary, hepatic, and renal impairment. Additionally, this group included individuals whose legal guardians had declined to participate in the study, as well as those who were lost to follow-up (i.e., those who had died). The intravertebral occupancy group : history of cranial surgery; history of cerebrovascular disease; and those who refused to participate in this study.

Design outcomes

Primary

MeasureTime frame
TMS-EEG;Coma Recovery Scale,CRS-R;

Secondary

MeasureTime frame
norepinephrine;adrenaline;

Countries

China

Contacts

Public ContactLan Yao

peking university international hospital

yaolan@pkuih.edu.cn+86 136 7101 0819

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026