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Effects of Repetitive Transcranial Magnetic Stimulation Combined with Repetitive Peripheral Magnetic Stimulation on Complete Postoperative Median Nerve Injury: Protocol of A Randomized Control Study

Effects of Repetitive Transcranial Magnetic Stimulation Combined with Repetitive Peripheral Magnetic Stimulation on Complete Postoperative Median Nerve Injury

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094038
Enrollment
Unknown
Registered
2024-12-16
Start date
2024-12-17
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative complete injury of the median nerve (cutting injury)

Interventions

Conventional intervention group:Basic treatment includes wax therapy, electronic biofeedback stimulation therapy, joint mobilization, nerve mobilization, dynamic and static orthosis therapy, sensory f
rPMS + sham rTMS group:Besides basic treatment, participants will receive rPMS intervention. In rPMS intervention, the therapist will fix the participant’s upper limb with one hand and hold the coil w
Sham rPMS + rTMS group:In rTMS intervention, participants will receive iTBS in M1 areas, with the parameters of 120% MT, 50 Hz in the cluster + 5 Hz outside the cluster, stimulation for 2 seconds, 8 s

Sponsors

Shanghai Jing'an District Central Hospital (Jing'an Branch of Huashan Hospital Affiliated to Fudan University)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) unilateral cutting injury below the elbow that affects only the median nerve; (2) age 18-60 years old; (3) within 3 months after surgical treatment, with an onset of no less than 3 weeks and a stable condition; (4) Sunderland grade V; (5) Mini-Mental State Examination (MMSE) score >=25.

Exclusion criteria

Exclusion criteria: (1) have a pacemaker; (2) have mental illness; (3) have a history of epilepsy; (4) metal implant on the involved side; (5) pregnancy; (6) refuse to participate in the study.

Design outcomes

Primary

MeasureTime frame
Grip strength;

Secondary

MeasureTime frame
Pinch;Sunderland grade;Semmes-Weinstein monofilament test (SW);Two-point discrimination test (2PD);Purdue pegboard test (PPT);Motor nerve conduction velocity test (MCV);Sensory nerve conduction velocity test (SCV);Functional near-infrared spectroscopy (fNIRS);

Countries

China

Contacts

Public ContactXianggui Chen

Shanghai Jing'an District Central Hospital (Jing'an Branch of Huashan Hospital Affiliated to Fudan University)

1213446704@qq.com+86 152 0191 8614

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026