Dry eye
Conditions
Interventions
Experimental Group:Wearing scleral lens
Sponsors
The First Affiliated Hospital of the Army Medical University of the People's Liberation Army
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Aged between 18 and 70, voluntarily participate in this clinical study, and sign the informed consent form. 2) Irregular astigmatism caused by moderate to severe dry eyes is not effective after conventional treatment, the specific manifestation is: after 2 weeks to 1 month of conventional treatment, there is no significant improvement in visual quality and subjective symptom scores of dry eye, as well as objective examination results. 3) Presenting with clinical symptoms and signs of dry eye, and the clinical examination meets the diagnostic criteria for moderate and severe dry eye in the "Chinese Dry Eye Expert Consensus: Definition and Classification (2020)": A.Moderate dry eye: Slit-lamp examination shows corneal damage involving no more than 2 quadrants and/or corneal fluorescein staining with >=5 spots and =2 seconds. B. Severe dry eye: Slit-lamp examination shows corneal damage involving more than 2 quadrants and/or corneal fluorescein staining with>=30 spots, with a tear breakup time (BUT) =23 points.
Exclusion criteria
Exclusion criteria: 1) Patients with fungal, bacterial or viral keratoconjunctivitis are clinically suspected to be active. 2) Patients with a history of eye surgery within the last 3 months or who plan to have eye surgery during the study period. 3) Patients who have previously undergone treatment with scleral lenses to correct irregular astigmatism. 4) Known allergic history of scleroscope materials used in this study. 5) Patients who, in the opinion of the physician, are not suitable for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular Surface Disease Index Scale(OSDI) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ocular surface score;Tear secretion;Tear break up time;Lipid layer thickness;Meibomian gland score;Central corneal thickness;Endothelial cell density;Aberration; | — |
Countries
China
Contacts
Public ContactYang Yulil
The First Affiliated Hospital of the Army Medical University of the People's Liberation Army
Outcome results
None listed