postherpetic neuralgia
Conditions
Interventions
esketamine:pulsed radiofrequency combined with esketamine for intravenous controlled analgesia
control group:pulsed radiofrequency combined with normal saline
Sponsors
Ningbo Medical Centre Lihuili Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.ZAP was diagnosed according to the Consensus of Chinese Experts on herpes zoster Diagnosis and Treatment, and the medical records were complete; 2.VAS score > 3; 3.Patients with shingles on the neck, chest, and lumbar;
Exclusion criteria
Exclusion criteria: 1.Long-term use of hormones; 2.Injection site infection; 3.Abnormal coagulation function; 4.Liver and kidney dysfunction; 5.Painful areas are associated with spinal tumors, fractures, and disc herniations; 6.Patients who do not cooperate and refuse treatment during the trial; 7.Lost visitor; 8.The patient refused to answer questions; 9.Local anesthetic toxicity occurred; 10.Pneumothorax, respiratory depressio; 11.Patients suffering from heart diseas; 12.respiratory disease;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of PHN;Use of analgesics (tramadol, gabapentin, or pregabalin);Adverse event rate;Central sensitization score;seurm BDNF;Daily living ability rating scale; | — |
Countries
China
Contacts
Public Contactyingying lou
Ningbo Medical Centre Lihuili Hospital
Outcome results
None listed