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A single-arm clinical trial on the safety and efficacy of laparoscopic radical proximal gastrectomy combined with anti-reflux biological flap technique

Laparoscopic radical proximal gastrectomy with biological flap function preserving surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094019
Enrollment
Unknown
Registered
2024-12-16
Start date
2024-01-17
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Cancer

Interventions

Biological flap technique group:Digestive tract reconstruction was performed with anti-reflux biological flap technique after laparoscopic radical proximal gastrectomy

Sponsors

The First Affiliated Hospital of Xi 'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age 20-80 years old, male or female; (2) Siewert type ?/? AEG confirmed by preoperative imaging and pathological biopsy; (3) tumor diameter <=4 cm; (4) Preoperative clinical stage: ct1-3N0-1M0; (5) no distant metastasis was found by preoperative chest X-ray, abdominal ultrasound or upper abdominal CT. (6) no contraindications to surgery; (7) Patients and their families voluntarily signed informed consent and participated in the study.

Exclusion criteria

Exclusion criteria: (1) patients with double primary tumors including gastric adenocarcinoma; (2) patients with severe chronic diseases or poor general conditions such as liver cirrhosis with massive ascites, insulin uncontrolled diabetes, heart, liver, lung, brain, kidney and other organ failure, coagulation dysfunction and cannot be corrected; (3) patients with immunodeficiency, immunosuppression or autoimmune diseases; (4) patients who refused to sign the informed consent form to participate in the study.

Design outcomes

Primary

MeasureTime frame
Incidence of reflux esophagitis and anastomotic stenosis at 12 months after surgery;Quality of life 12 months after surgery;Complication rate;

Secondary

MeasureTime frame
Operative time;Postoperative nutritional status;

Countries

China

Contacts

Public ContactLin Fan

The First Affiliated Hospital of Xi'an Jiaotong University

linnet@xjtu.edu.cn+86 137 0919 0151

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026