Age-related cataract
Conditions
Interventions
Age-related cataract group(self controlled):None
Sponsors
Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Subjects were clinically diagnosed with bilateral age-related cataract; 2. Consented to participate in the study; 3. Between 50 and 70 years old and with a certain level of understanding;
Exclusion criteria
Exclusion criteria: 1. The subject has age-related cataracts combined with other ophthalmic diseases. 2. The subject has a history of ocular surgery or ocular trauma. 3. The subject has systemic diseases such as diabetes, hyperthyroidism, mental illness, autoimmune diseases, etc. 4. The subject is unable to cooperate in completing the assessment. 5. The subject is a pregnant or lactating woman. 6. The subject is participating in other ophthalmic clinical trials during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The severity of cataracts is classified according to the LOCS III grading system;Facial anatomical data; | — |
Secondary
| Measure | Time frame |
|---|---|
| Handedness;Dominant eye;Expression of circRNA;Reactive oxygen species (ROS) in the anterior capsule;Glutathione (GSH) in the anterior capsule; | — |
Countries
China
Contacts
Public ContactAnpeng Pan
Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University
Outcome results
None listed