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Influence of oliceridine on catheter-related bladder discomfort in male patients undergoing transurethral surgery: A single-center, randomized, controlled trial

Influence of oliceridine on catheter-related bladder discomfort in male patients undergoing transurethral surgery

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400094009
Enrollment
Unknown
Registered
2024-12-16
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative catheter-related bladder discomfort

Interventions

Oxelidine Group (Group F):Oxelidine 1mg was given to the patient before the end of surgery
Morphine group (M group):Morphine 2 mg was given to the patient before the end of surgery

Sponsors

Chengdu Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Male patients aged 18-79 years, including cut-off values; 2. Patients undergoing transurethral bladder, prostate and ureteral lithotripsy under elective general anaesthesia; 3. ASA grading I to III; 4. Those who can accurately understand pain assessment methods; 5. The estimated operation time is less than 3 hours, and it is planned to be extubated in the operating room and sent back to the observer of the anaesthesia and resuscitation room (Postanaesthesia Care Unit, PACU) after the operation; 6. Patients with moderate and severe CRBD after waking up after operation; 7. Patients voluntarily participated in this trial and signed a written informed consent form.

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Chronic pain before operation; 2. Preoperative acute and chronic renal insufficiency and liver insufficiency (preoperative serum ALT and AST values increased by more than 2 times the upper limit of normal value); 3. Body mass index (BMI) > 35 kg/m^2 or body weight < 40 kg; 4. Frequent urination and urgency before surgery (excluding frequent urination and urgency caused by enlarged prostate in patients undergoing prostate surgery); 5. Bladder perforation occurred during operation; 6. History of opioid allergy.

Design outcomes

Primary

MeasureTime frame
Incidence of moderate to severe catheter-related bladder discomfort;

Secondary

MeasureTime frame
NRS score;CRBD severity classification;BPI score;Qor-15 score;

Countries

China

Contacts

Public ContactJiang Rongjun

Chengdu Second People's Hospital

rongjuanjiang@163.com+86 185 0287 6250

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026