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Research on the Correlation between Varus Deformity and Anterior Cruciate Ligament Deficiency in Knee Osteoarthritis

Research on the Correlation between Varus Deformity and Anterior Cruciate Ligament Deficiency in Knee Osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400093967
Enrollment
Unknown
Registered
2024-12-15
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

KOA

Interventions

Gold Standard:Take the state of the anterior cruciate ligament observed during knee arthroplasty as the gold standard,and it is divided into 5 grades: Grade 1: The anterior cruciate ligament is still
Grade 2: The synovial part of the anterior cruciate ligament is damaged or disappeared
Grade 3: The fiber bundles are exposed and appear in bundles
Grade 4: The continuity of the fiber bundles exists, but there is a lack of strength when stretched
Grade 5: Part of the fiber bundles of the anterior cruciate ligament are ruptured or disappeared. Grades 4-5 indicate anterior cruciate ligament Deficiency.
Index test:The distal femoral lateral mechanical axis angle, proximal tibial medial mechanical axis angle, distal femoral lateral anatomical angle, proximal tibial medial anatomical angle, hip-knee-an
the femorotibial angle and tibiofemoral joint line angle on the valgus stress radiographs of the knee joint
the maximum wear point of the proximal tibia on the lateral radiographs of the knee joint
the grading of the anterior cruciate ligament on MRI of the knee joint.

Sponsors

Wangjing Hospital of China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Between 50 and 85 years old, with no limitation on gender. 2.Having been previously diagnosed with knee osteoarthritis. 3.Having received knee arthroplasty treatment in the Second Department of Bone and Joint of Wangjing Hospital. 4.The preoperative symptom was localized pain in the medial compartment of the knee joint. 5.On the preoperative weight-bearing X-ray films of the lower extremities, the medial compartment of the knee joint was significantly narrowed compared to the lateral compartment, or even disappeared. 6.Medical record data is complete.

Exclusion criteria

Exclusion criteria: 1.With a history of trauma in the knee joint. 2.With a history of other surgeries on the knee joint. 3.Secondary knee arthritis, such as rheumatoid knee arthritis or infectious knee arthritis. 4.With a medial collateral ligament tear. 5.Medical record data is incomplete.

Design outcomes

Primary

MeasureTime frame
accuracy;sensibility;specificity;positive predictive value;negative predictive value;positive likelihood ratio;negative likelihood ratio;Receiver Operating Characteristic curve;

Countries

China

Contacts

Public ContactZheng zhongzhou

Wangjing Hospital of China Academy of Chinese Medical Sciences

1741108562@qq.com+86 134 6655 6441

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026