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Co-occurrence patterns of immune-related adverse events across multiple organs and their clinical outcomes: a multi-center cohort study

Co-occurrence patterns of immune-related adverse events across multiple organs and their clinical outcomes: a multi-center cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400093959
Enrollment
Unknown
Registered
2024-12-13
Start date
2024-12-15
Completion date
Unknown
Last updated
2024-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Interventions

Case series:None

Sponsors

Affiliation of the Registrant: Cancer Hospital, Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients with a confirmed diagnosis of malignant tumors who are undergoing or about to undergo immunotherapy. 2.Age >= 18 years. 3.Voluntarily participating and signing an informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients with unclear pathological diagnosis or those who have been ruled out for malignant tumors after examination and treatment. 2.Patients who have completed 4 or fewer cycles of immunotherapy and have explicitly decided not to proceed with further treatment. 3.Patients who have completed immunotherapy outside the hospital and lack assessment of adverse reactions.

Design outcomes

Primary

MeasureTime frame
Immune checkpoint inhibitor-related endocrine toxicity;Immune checkpoint inhibitor-related hepatotoxicity;Immune Checkpoint Inhibitor-related Gastrointestinal Toxicity;Immune Checkpoint Inhibitor-Related Pulmonary Toxicity;

Secondary

MeasureTime frame
Immune Checkpoint Inhibitor-Related Osteoarticular and Myotoxicity;Immune Checkpoint Inhibitor-Related Skin Toxicity;Immune Checkpoint Inhibitor-Related Cardiovascular Toxicity;Immune Checkpoint Inhibitor-Related Neurotoxicity;Immune Checkpoint Inhibitor-Related Nephrotoxicity;Immune checkpoint inhibitor-related reactive cutaneous capillary angiomatosis;Immune checkpoint inhibitor-related pancreatic toxicity;Immune checkpoint administrator-related hematological toxicity;Immune checkpoint inhibitor-associated ophthalmic adverse events;Immune checkpoint inhibitor-related ototoxicity;Immune checkpoint inhibitor-related cystitis;

Countries

China

Contacts

Public ContactMinghua Cong

Affiliation of the Registrant: Cancer Hospital, Chinese Academy of Medical Sciences

congmh@cicams.ac.cn+86 150 0104 8699

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026