Postoperative Pain
Conditions
Interventions
Test group:Postoperative analgesia was administered using a patient-controlled intravenous analgesia pump. The experimental group received a postoperative analgesia formula consisting of 159.5ml of 0.
Control group:The postoperative analgesic formula for the control group: 180ml of 0.9% sodium chloride injection+15mg of tropisetron+150ug of sufentanil citrate injection. The analgesic pump parameter
Sponsors
Sichuan Provincial Orthopedic Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Single site traumatic fracture of lower limbs; 2. 18 years old <= age <= 75 years old, gender not limited; 3. ASA classification levels I-III; 4. Understand the research protocol and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Known or suspected multiple injuries; 2. Known or suspected to have serious infectious diseases; 3. History of opioid allergy; 4. Use drugs that may affect analgesic response (central alpha adrenergic, antiepileptic drugs, neurostimulants, antidepressants, or antipsychotics), with no fixed dose administered for >= 30 days before surgery; 5. Use oral or parenteral corticosteroids within 3 months before surgery; 6. Patients with liver and kidney dysfunction during screening, and with Child Pugh classification of liver function not reaching A or B after treatment, as well as creatinine levels greater than 158 µ mol/L; 7. Other postoperative exclusion criteria include evidence of hemodynamic instability or respiratory dysfunction, surgical/anesthesia complications, and events that may affect data interpretation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nausea;Vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| pain score;Sedation rating;Sleep quality score;Types and dosages of remedial antiemetic and analgesic drugs; | — |
Countries
China
Contacts
Public ContactLi Su
Sichuan Provincial Orthopedic Hospital
Outcome results
None listed