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Effect of head and neck location on cardiovascular response to double-lumen bronchial tube intubation and sufentanil ED50

Effect of head and neck location on cardiovascular response to double-lumen bronchial tube intubation and sufentanil ED50

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093953
Enrollment
Unknown
Registered
2024-12-13
Start date
2025-01-15
Completion date
Unknown
Last updated
2024-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic surgery

Interventions

Neutral group:Go to the pillow and lie flat with the occipital bone close to the operating table
Head elevation group:A pillow is placed under the head so that the person elevates the head until the external auditory canal and sternal notch are in the same horizontal plane

Sponsors

Guangdong Provincial Hospital of Chinese Medicine, Hainan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Age 18-65 years old; (2) Thoracic surgery patients undergoing general anesthesia at the scheduled date; (3) American Society of Anesthesiologist (ASA) grade I-III; (4) Gender is not limited; (5) non-emergency surgery; (6) Obtain informed consent from patients and sign the informed consent form.

Exclusion criteria

Exclusion criteria: Patients who are expected to have a difficult airway; cervical spondylosis; history of preoperative hoarseness, bronchial asthma, airway hyperresponsiveness; Preoperative liver function, renal function abnormalities, cardiac insufficiency, heart rate and arrhythmia and coronary heart disease; Patients with a history of cognitive dysfunction and psychiatric disorders.

Design outcomes

Primary

MeasureTime frame
Single-use double-lumen tube intubation success rate;Sufentanil ED50 for double-lumen bronchial tube intubation;

Secondary

MeasureTime frame
Basic information of the patient (age, height, weight, etc.);ASA grading;Blood pressure;heart rate;BIS values;Remifentanil salvage dose;Time taken for intubation;Number of intubation attempts;Other operational requirements for laryngeal exposure (lifting force or laryngeal compression);To assess the incidence of velopharyngeal mucosal injury after endotracheal intubation;Incidence of postoperative sore throat;Incidence of postoperative hoarseness;

Countries

China

Contacts

Public ContactWangtiantian

Guangdong Provincial Hospital of Chinese Medicine, Hainan Hospital

245175099@qq.com+86 187 7672 6190

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026