In 2018, new recommendations for naming anesthesia and surgery-related cognitive changes recommended perioperative neurocognitive impairment (PND) as an umbrella term for perioperative cognitive decline, These included acute postoperative delirium (POD), delayed neurocognitive recovery (within 30 days of recovery, dNCR), and postoperative neurocognitive dysfunction (expected recovery 30 days to 12
Conditions
Interventions
False transcranial direct current stimulation group:Sham transcranial direct current stimulation
Sponsors
The First Hospital Of Jiaxing
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age ? 60 2. ASA level 3 (3) or less than big heart surgery patients (including the abdomen, chest, orthopaedic surgery for more than 2 h); 2. ASA level 3; 3.or less than big heart surgery patients (including the abdomen, chest, orthopaedic surgery for more than 2 h);
Exclusion criteria
Exclusion criteria: 1 patients refused to sign the consent form; 2 the scalp infection; 3. Severe disease of heart head blood-vessel. 4. Metal implants in vivo; 5. Lost to follow-up;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of PND within 3 months after surgery in both groups; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum S100ß, tau protein;The postoperative Hospital Anxiety and Depression Scale anxiety (HDS-A) subscale was used to measure perioperative anxiety. Pain rating Scale (NRS); Frailty score (index of fatigue, resistance, walking, illness, and weight loss); Sleep quality score (Pittsburgh Sleep Quality Index [PSQI]).; | — |
Countries
China
Contacts
Public ContactHuadong Ni
The First Hospital Of Jiaxing
Outcome results
None listed