Regional Block
Conditions
Interventions
Single-liposome cohort (prospective cohort):Preoperative bilateral subcostal anterior quadratus lumborum block, with a single-shot of 133mg liposomal bupivacaine (Jiangsu Hengrui, China) diluted to 30
Intermittent-ropivacaine cohort (retrospective cohort):Preoperative bilateral subcostal anterior quadratus lumborum block with catheter placement , with a single preoperative administration of 0.3% ro
Sponsors
Beijing Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Ages 18-80 years old; 2.Anticipated radical gastrectomy for gastric cancer.
Exclusion criteria
Exclusion criteria: 1.Unable to cooperate with pulmonary function tests; 2.Comorbid with myasthenia gravis or Parkinson's disease; 3.New York Heart Association functional classification III-IV; 4.American Society of Anesthesiologists (ASA) physical status classification III-V; 5.Complex surgery or combined with other site surgeries; 6.Consciousness disturbance; 7.Refusal to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference of average resting pain scores among three days between cohorts; | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of daily resting pain scores between cohorts over three days postoperatively;Comparison of daily cough-related pain scores between cohorts over three days postoperatively;Comparison of average cough-related pain scores between cohorts over three days postoperatively;Thermal hypoesthesia level after a single dose of liposomal bupivacaine following nerve block at 1 hour ; | — |
Countries
China
Contacts
Public ContactZongyang Qu
Beijing Hospital
Outcome results
None listed