adenomyosis
Conditions
Interventions
Group of best response to GnRHa :none
Group of poor response to GnRHa :none
Sponsors
Obstetrics and Gynecology Hospital of Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Adenomyosis was diagnosed according to clinical manifestations and MRI; 2. 18 to 55 years old, regular menstrual cycle (21 to 35 days); 3. The IUD has not been implanted in the past 3 years and the female/progesterone therapy has not been received within 3 ;months before this treatment, and GnRH-a therapy is to be performed for 3 months.
Exclusion criteria
Exclusion criteria: 1. Suspected or confirmed gynecological malignancy; 2. Combined with genital tract malformations or pelvic inflammatory diseases; 3. Combined with thyroid dysfunction or polycystic ovary syndrome (PCOS); 4. Adenomyopathy was excluded by pathological examination after total hysterectomy or focal resection; 5. GnRH-a was not applied before operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Uterine volume reduction rate;Lesion size reduction rate;Degree of anemia improvement; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain relief;Grading of menstrual volume;decline of Serum CA125;decline of Serum estradiol ;endometriosis health profile-5, EHP-5; | — |
Countries
China
Contacts
Public ContactYi Xiaofang
Obstetrics and Gynecology Hospital of Fudan University
Outcome results
None listed