Postoperative sleep disorders
Conditions
Interventions
Experimental group:Preoperative oral administration of midazolam oral solution 0.16mg/kg
Control group:Oral placebo 10% glucose 5ml
Sponsors
Affiliated Hospital of Guizhou Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients undergoing gynecological laparoscopic surgery under elective general anesthesia; 2.Age range: 18-65 years old; 3.ASA levels I-III; 4.Preoperative anxiety PAS score greater than or equal to 8 points 5.Patients voluntarily participate in the study
Exclusion criteria
Exclusion criteria: 1. Individuals with a history of severe heart, brain, lung, liver, kidney, and metabolic diseases; 2. Patients with respiratory diseases such as asthma and chronic obstructive pulmonary disease in the past; 3.History of acute respiratory inflammation within 2 weeks without cure; 4.Long term use of analgesics, sedatives, and antipsychotic drugs; 5.Individuals with neurological and muscular disorders, as well as mental illnesses; 6.Individuals known to be allergic to emulsions, benzodiazepines, and opioids; 7.Predicting those who may experience or have experienced difficult airways; 8.Those who are uncooperative and unable to communicate; 9.Patients currently participating in other clinical trials; 10.Patients who have been diagnosed with diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative night sleep monitoring results on the day and the second day;Athens Insomnia Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Restoration Quality Assessment (Restoration Quality Scale QOR-15);Anxiety score (PAS score) and Ramsay sedation score 10 minutes before anesthesia;; The dosage of sedative and analgesic drugs during surgery;Wake-up time; The time from patient discontinuation of medication to extubation;Pain Scale (VAS) score;Patient satisfaction score;;Postoperative adverse reactions or complications; Nausea, vomiting, drowsiness, delirium, dizziness, other adverse reactions, etc; ;Postoperative hospitalization time.; | — |
Countries
China
Contacts
Public ContactXiaohua Zou
Affiliated Hospital of Guizhou Medical University
Outcome results
None listed