Colorectal cancer
Conditions
Interventions
T cell senescence group:None
Non-T cell senescence group:None
Sponsors
Beijing Friendship Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 79 Years
Inclusion criteria
Inclusion criteria: (1) The age range should be from 65 to 79 years old; (2) The ASA classification should be grade II-III; (3) Individuals must undergo laparoscopic radical surgery for colorectal cancer.
Exclusion criteria
Exclusion criteria: Exclusion criteria: If any of the following conditions are met by patients, they will be excluded from participating in this research: (1) Patients who decline to take part in the research; (2) Patients who lack the ability to communicate due to impaired consciousness or neurological or psychiatric disorders; (3) Patients having contraindications for any drugs or techniques employed in this research; (4) Patients with a history of dependence on alcohol or drugs; (5) Body Mass Index (BMI) falls outside the range of 18-25; (6) Individuals lacking literacy skills; (7) Patients experiencing chronic pain that has not been effectively managed for at least one month; (8) Individuals exhibiting severe abnormalities in heart, lung, liver, kidney, or brain function; (9) Immunocompromised patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of QoR15(24 hours after surgery); | — |
Secondary
| Measure | Time frame |
|---|---|
| The proportion of QoR15 (48 hours after surgery, and 72 hours after surgery);The percentage of patients with good recovery quality at 24 hours postoperatively (QoR15 >120);VAS rating at rest and during movement (24 hours after surgery, 48 hours after surgery, and 72 hours after surgery) ;consumption of opioids (within the first 24 hours, 48 hours, and 72 hours postoperatively);rate of rescue analgesia;Incidence of nausea in the first three days after surgery;Incidence of vomiting in the first three days after surgery;Incidence of delirium in the first three days after surgery;Emergence agitation during the recovery period;Anesthesia recovery time;Extubation time ;Exhaust time ;Time to get out of bed after surgery;Postoperative hospitalization time; | — |
Countries
China
Contacts
Public ContactWang Yun
Department of Anaesthesiology, Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed