chronic liver disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18-80 years old, without gender restrictions, who have been hospitalized in The First Affiliated Hospital of Guangdong Pharmaceutical University from December 1, 2016 to May 31, 2024 and diagnosed with chronic liver diseases, including hepatitis, fatty liver, liver cirrhosis, liver cancer and their subordinate diagnoses, with other disease diagnoses but do not need special treatment for the time being and do not affect the relevant data of this topic, such as gastric disease, irritable bowel syndrome, etc.; Have twice or more blood test results;
Exclusion criteria
Exclusion criteria: Escalation or de-escalation of anticoagulation or procoagulation regimen within 1 month prior to each blood draw; Plasma transfusion therapy within 1 month before each blood draw; Acute bleeding during the observation period, such as gastrointestinal bleeding, variceal bleeding, traumatic bleeding, etc.; Uncontrollable infection, use of antibiotics, etc. during the observation period; The interval between blood tests is too long (more than 180 days); Children and adolescents under the age of 18; Pregnant or lactating women, patients with a large amount of ascites;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| prothrombin time(PT);activated partial thromboplatin time(APTT);thrombin time(TT);fibrinogen(FIB);international normalized ratio(INR);prothrombin time activity(PTA); | — |
Secondary
| Measure | Time frame |
|---|---|
| platelet(PLT);white blood cell(WBC);alanine aminotransferase(ALT);aspartate aminotransferase(AST);PCT; | — |
Countries
China
Contacts
The First Affiliated Hospital of Guangdong Pharmaceutical University