Skip to content

Washed Microbiota Transplantation impact on coagulation parameter of Chronic Liver Disease patient

Washed Microbiota Transplantation impact on coagulation parameter of Chronic Liver Disease patient

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400093882
Enrollment
Unknown
Registered
2024-12-13
Start date
2024-12-16
Completion date
Unknown
Last updated
2024-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic liver disease

Interventions

WMT group:none
non-WMT group:none
WMT-normal group:none

Sponsors

The First Affiliated Hospital of Guangdong Pharmaceutical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients aged 18-80 years old, without gender restrictions, who have been hospitalized in The First Affiliated Hospital of Guangdong Pharmaceutical University from December 1, 2016 to May 31, 2024 and diagnosed with chronic liver diseases, including hepatitis, fatty liver, liver cirrhosis, liver cancer and their subordinate diagnoses, with other disease diagnoses but do not need special treatment for the time being and do not affect the relevant data of this topic, such as gastric disease, irritable bowel syndrome, etc.; Have twice or more blood test results;

Exclusion criteria

Exclusion criteria: Escalation or de-escalation of anticoagulation or procoagulation regimen within 1 month prior to each blood draw; Plasma transfusion therapy within 1 month before each blood draw; Acute bleeding during the observation period, such as gastrointestinal bleeding, variceal bleeding, traumatic bleeding, etc.; Uncontrollable infection, use of antibiotics, etc. during the observation period; The interval between blood tests is too long (more than 180 days); Children and adolescents under the age of 18; Pregnant or lactating women, patients with a large amount of ascites;

Design outcomes

Primary

MeasureTime frame
prothrombin time(PT);activated partial thromboplatin time(APTT);thrombin time(TT);fibrinogen(FIB);international normalized ratio(INR);prothrombin time activity(PTA);

Secondary

MeasureTime frame
platelet(PLT);white blood cell(WBC);alanine aminotransferase(ALT);aspartate aminotransferase(AST);PCT;

Countries

China

Contacts

Public ContactLi-Hao Wu

The First Affiliated Hospital of Guangdong Pharmaceutical University

wulihao@gdpu.edu.cn+86 136 6063 5861

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026