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Clinical efficacy and safety of Vibrating Mesh Nebulization in the treatment of neonatal severe pneumonia

Clinical efficacy and safety of Vibrating Mesh Nebulization in the treatment of neonatal severe pneumonia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093867
Enrollment
Unknown
Registered
2024-12-12
Start date
2025-01-20
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe neonatal pneumonia

Interventions

Vibrating Mesh Nebulizer Group:Use Vibrating Mesh Nebulizer for treatment
Control group:Use compressed air nebulizer for treatment

Sponsors

Fujian Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Meet the clinical diagnostic criteria of severe neonatal pneumonia in the 5th edition of Practical Neonatology; 2. receiving mechanical ventilation supportive therapy; 3. The gestational age at birth >= 37 weeks, the birth weight >= 2500g, and the age < 28 days.

Exclusion criteria

Exclusion criteria: 1. Patients suffer from congenital respiratory diseases such as larynx, bronchi, lung and thoracic dysplasia or malformation; 2. Patients with respiratory failure due to heart disease or nervous system disease; 3. Patients with severe hypotension, shock, ventricular or supraventricular arrhythmia accompanied by hemodynamic instability; 4. Those who are allergic to nebulized drugs.

Design outcomes

Primary

MeasureTime frame
Duration of mechanical ventilation;

Secondary

MeasureTime frame
Sputum viscosity;Occurrence of adverse reactions;

Countries

China

Contacts

Public ContactLin Jiajia

Fujian Children's Hospital

119677043@qq.com+86 158 8003 2623

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 9, 2026