Ischemic stroke
Conditions
Interventions
experimental group:iTBS combined with MI-BCI intervention training
control group A:sham iTBS combined with MI-BCI intervention training
control group B:iTBS combined with lower limb motomed intervention training
Sponsors
Department of Rehabilitation,Zhujiang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) In accordance with the "Diagnostic criteria for Cerebrovascular Diseases" formulated by the Fourth Academic Conference on Cerebrovascular Disease of the Chinese Medical Association, and diagnosed as unilateral cerebral hemispheric ischaemic stroke confirmed by cranial CT or MRI; (2) First-ever onset of the disease, with no previous history of stroke, aged 30-75 years old, and 2 weeks-6 months after the onset of the disease; (3) Mini-mental Status Examination (MMSE): 21-27 points; (4) Brunnstrom Hemiplegia Motor Function Assessment >= stage I; (5) Patients' vital signs were stable, without obvious communication and comprehension disorders, and able to cooperate in completing the treatment and assessment; (6) Patients signed the informed consent form by themselves or authorised a delegate to sign the form.
Exclusion criteria
Exclusion criteria: (1) with pacemakers, metal objects, metal implants, cochlear implants, and hearing assistive devices; (2) with a history of previous cranial surgery and severe cranial defects that interfere with the wearing of the EEG cap; (3) with increased intracranial pressure; (4) with a history of epilepsy and a family history of epilepsy; (5) with severe organic diseases such as combined cardiac, hepatic, and renal disorders; (6) with significant aphasia, hearing impairment, and visual field impaired; (7) undergoing other central neuromodulation training; (8) pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment Lower Extremity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment;functional ambulation category scale;Functional near-infrared spectroscopy;resting-stating EEG; | — |
Countries
China
Contacts
Public ContactWen Wu
Zhujiang Hospital of Southern Medical University
Outcome results
None listed