Postoperative delirium (POD)
Conditions
Interventions
Propofol general anesthesia group:Propofol general anesthesia
Rimazolen general anesthesia group:Rimazolen general anesthesia
Sponsors
The First Hospital Of Jiaxing
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.This study included patients who underwent non cardiac surgery under general anesthesia with endotracheal intubation from January 2025 to December 2026, with a surgical duration of>60 minutes, aged >= 60 years, ASA I-III grade, and had stayed in the hospital for at least 72 hours after surgery. The study has been reviewed and approved by the hospital ethics committee, and all included patients have signed informed consent forms.
Exclusion criteria
Exclusion criteria: 1.The surgery is only performed under local anesthesia, regional anesthesia, or anesthesia monitoring; 2.Patients with previous mental illnesses, preoperative use of antipsychotic drugs, and alcohol withdrawal delirium; 3.Patients with second degree type 1 or above atrioventricular block, or acute myocardial infarction or stroke within 3 months; 4.Patients with severe liver and kidney diseases (Child pugh C grade liver, serum creatinine>442umol/L); 5.Patients with ASA grade IV or higher; 6.Patients who are allergic to any drugs related to the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neurofilamentlightchain;Indicators of delirium; | — |
Countries
China
Contacts
Public ContactZhou Qinghe
The First Hospital Of Jiaxing
Outcome results
None listed