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Ethanol ablation versus ethanol combined with microwave ablation for treating different component large cystic thyroid nodules: a randomized clinical trial

Ethanol ablation versus ethanol combined with microwave ablation for treating different component large cystic thyroid nodules: a randomized clinical trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093861
Enrollment
Unknown
Registered
2024-12-12
Start date
2024-04-08
Completion date
Unknown
Last updated
2024-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thyroid cyst

Interventions

Ethanol ablation group:The patients in this group were treated with ethanol ablation
Combination group:The patients in this group were treated with ethanol combined with microwave ablation.

Sponsors

Beijing Friendship Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with cystic thyroid nodules (cystic component > 90%), the maximum diameter of nodules > 3 cm; 2. Patients refused surgical treatment; 3. Compression symptoms caused by thyroid nodules or cosmetic problems; 4. Serum thyroid hormone, thyrotropin and calcitonin levels are normal; 5. WIithout heart, lung, brain, kidney and coagulation system diseases, anesthesia contraindication and surgical contraindications; 6. Willing to participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. The nodules showed malignant ultrasonic signs (i.e., aspect ratio > 1, burr sign, obvious hypoechoic, small or large calcification). 2. Patients with anhydrous alcohol allergy and preoperative thyroid dysfunction, coagulation dysfunction ; 3. Under the age of 18; 4. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
volume reduction ratio;

Secondary

MeasureTime frame
treatment success rate;the level of thyroid hormone ;the score of beauty;the score of blood flow;clinical symptoms;postoperative ultrasonography;operative complication;

Countries

China

Contacts

Public ContactLinxue Qian

Beijing Friendship Hospital, Capital Medical University

qianlinxue2002@163.com+86 133 1110 0999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026