Hyperuricacidemia
Conditions
Interventions
Allopurinol group:Oral allopurinol : the initial dose of 50 mg / time, 1 ~ 2 times / day, weekly increase of 50 ~ 100 mg / day, to 200 ~ 300 mg /day, divided into 2 ~ 3 times. The maximum dose was no
BMY group:The dosage and taking method of " Baimao Decoction ": Baimao Decoction ( The prescription contains crude drug Baimaogen 45 g, Danggui 20 g, Jinqiancao 60 g, Juemingzi 10 g, Shanzha 10 g, whi
Sponsors
Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Western medicine diagnosis: according to the health industry standard of the People's Republic of China - dietary guidance for patients with hyperuricemia and gout (WS/T 560-2017): under normal diet, fasting blood was collected twice on the same day, and the biochemical indexes were measured by uricase method: blood uric acid was higher than 420 µmol/L in men and 360 µmol/L in women. Traditional Chinese Medicine Diagnosis: The "Diagnostic Criteria for the Efficacy of Traditional Chinese Medicine Syndromes" in the "Traditional Chinese Medicine Industry Standards of the People's Republic of China", "Traditional Chinese Medicine Diagnostic Efficacy Standards for Internal Diseases" and "Traditional Chinese Medicine Industry Standards of the People's Republic of China" were adopted, and patients who met the criteria for damp heat and stasis were included in the scope of the study. 1. Patients with hyperuricemia who meet the diagnostic criteria of Western medicine; 2. Patients with hyperuricemia who meet the diagnostic criteria of traditional Chinese medicine; 3. Patients with hyperuricemia between the ages of 20-60 years with relatively stable blood pressure (within the standard range).range ).
Exclusion criteria
Exclusion criteria: 1. Patients who had taken antibiotics in the past three months ; 2.Factors that may affect the changes of intestinal flora such as gastrointestinal diseases and metabolic diseases ; 3. Diabetes, hyperthyroidism, liver and kidney dysfunction and various cancers after radiotherapy or chemotherapy that can lead to nucleic acid metabolism ; 4. Renal non-gout stones, renal failure and other kidney diseases ; 5. Recent use of dihydrocortisone, pyrazinamides and other drugs that can promote the excretion of uric acid. 6.Alcoholism, mental illness and pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood uric acid;Serum creatinine;Blood urea nitrogen;Intestinal flora;Uric acid in the urine;Urine volume; | — |
Countries
China
Contacts
Public ContactJianping Wang
Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine
Outcome results
None listed