Neonatal Acute Respiratory Distress Syndrome
Conditions
Interventions
Case series:No intervention
Sponsors
Shenzhen Nanshan Maternity and Child Healthcare Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 3 Years
Inclusion criteria
Inclusion criteria: 1. Study Population: (1) Term infants: For neonates with a gestational age of >= 40 weeks, the evaluation period is defined as the interval from birth to 4 weeks postnatally. For neonates with a gestational age = 16. 7. Hospitalization duration > 24 hours. 8. Informed consent signed by the guardian.
Exclusion criteria
Exclusion criteria: 1.RDS due to primary surfactant deficiency (such as hyaline membrane disease), transient tach(1) Congenital malformations: Such as congenital pulmonary airway malformation (CPAM) or diaphragmatic hernia. 2. Hereditary defects: ARDS-like clinical manifestations caused by surfactant protein (PS) deficiency due to genetic defects. 3. NRDS and TTN. 4. Termination of treatment: Cases where treatment was abandoned by the family or the infant died within 24 hours of birth due to familial decisions. 5. Guardians did not sign the informed consent form at the time of enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival at 28 days from NARDS diagnosis;Survival at 3 years of follow up; | — |
Secondary
| Measure | Time frame |
|---|---|
| risk factors for ARDS;bronchopulmonary dysplasia (BPD);air leak;massive pulmonary hemorrhage;retinopathy of prematurity (ROP);the incidence of NEC in infants with neonatal ARDS;intraventricular hemorrhage;sepsis;neurodevelopmental impairment (NDI);serious respiratory morbidity (SRM);growth restriction; | — |
Countries
China
Contacts
Public ContactZhang Ruolin
Shenzhen Nanshan Maternity and Child Healthcare Hospital
Outcome results
None listed