Management of acne scars by sequential combination of micro-needle radiofrequency followed by fractional CO2 laser versus each therapy alone

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400093848

Enrollment

Unknown

Registered

2024-12-12

Start date

2022-11-07

Completion date

Unknown

Last updated

2024-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne scar

Interventions

CO2 fractional laser group:Carbon dioxide fractional laser therapy

Microneedle Radiofrequency group:Invasive microneedle radiofrequency treatment

Combination treatment group:CO2+MNRF

Eligibility

Sex/Gender

All

Age

21 Years to 28 Years

Inclusion criteria

Inclusion criteria: Forty-five patients suffering from various forms and severity of acne scars (box scar, ice pick scar, atrophic, and rolling atrophic scar).

Exclusion criteria

Exclusion criteria: Active acne lesions, hypertrophic and keloid scars, active herpes simplex, immunocompromised individuals, breast-feeding or pregnancy, recent isotretinoin use, coagulation issues, heart problems, and rejection of post-treatment evaluation were among the exclusion criteria.

Design outcomes

Primary

Measure	Time frame
Improvement of acne scar ( acne scoring system);	—

Secondary

Measure	Time frame
Subjects' satisfaction with efficacy and safety;Efficacy Index;Adverse reactions (such as erythema, edema, crusting, pigmentation, infection, new scars, etc.) and their incidence;	—

Countries

Iraq

Contacts

Public ContactMohammed N. Al Mallah

University of Mosul

qasimalchalabi@uomosul.edu.iq+964 770 161 8688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026