Hip fracture
Conditions
Interventions
Individualized treatment group:Individualized blood pressure management
Standard treatment group:Routine blood pressure management
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with unilateral hip fracture; 2. 85> age>=65 years; 3. American Society of Anesthesiologists (ASA) grades I-III; 4. Unilateral hip fracture treatment under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Presence of severe untreated or medically uncontrolled hypertension (SBP>=180mmHg or DBP>=110mmHg); 2. Presence of acute cardiovascular and cerebrovascular events (acute myocardial infarction, heart failure, acute cerebral infarction, etc.) before surgery; 3. Continuous infusion of vasopressor drugs before entering the operating room; 4. Presence of psychiatric or neurological diseases; 5. Patients with severe cardiovascular system diseases, severe liver and kidney insufficiency and other systemic diseases; 6. Patients participating in other clinical studies; 7. Patient's refusal to sign informed consent; 8. Patients with bilateral hip fractures or multiple fractures; 9. Age>=85 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patients had at least one organ system (including renal, respiratory, cardiovascular, and nervous system) functioning 7 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of occurrences of intraoperative hypotension and hypertension in patients;The number of occurrences of bradycardia;Patient's total intraoperative output (blood loss, urine output);Patient's total intraoperative fluid volume;Patient's postoperative pain score;Patients have postoperative complications of various systems (respiratory, renal, digestive, cardiovascular, nervous system, etc.);The patient's postoperative ICU stay and total length of hospital stay;Patients had 30-day postoperative all-cause mortality; | — |
Countries
China
Contacts
Public ContactShaozhong Yang
Qilu Hospital of Shandong University
Outcome results
None listed