atrial fibrillation
Conditions
Interventions
vHPSD group:high power, short duration ablation
CPCD group:Conventional power, conventional duration ablation
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Patients with paroxysmal atrial fibrillation occurring at least once within six months or persistent atrial fibrillation lasting less than one year; 2.the patient or his guardian was informed of the nature of the trial and agreed to participate in all the terms of the trial, voluntarily signed the informed consent approved by the ethics committee; 3. age >= 18 years old, <= 75 years old; 4.agreed to accept the postoperative treatment plan and follow-up requirements, and was able to complete the follow-up and follow-up inspection requirements; 5.Poor efficacy or intolerance after treatment with at least one antiarrhythmic drug (such as amiodarone, propafenone, sotalol, dronedarone, etc.); Or patients who have obvious symptoms, and are still willing to undergo ablation surgery without medication.
Exclusion criteria
Exclusion criteria: 1. Rheumatic heart disease or pulmonary vein stenosis or previous implantation of pulmonary vein stents; 2. heart failure patients with cardiac function grade IV (NYHA); 3. Patients with myocardial infarction within 90 days before operation; 4. Individuals with a history of cardiac or PCI surgery within 90 days prior to ablation; 5. patients with stroke or transient ischemic attack (TIA) within 120 days; 6. thrombus in left atrium (LA) or left atrial appendage (LAA) according to TTE; 7. reversible causes of atrial fibrillation, including but not limited to uncontrolled hyperthyroidism, severe obstructive sleep apnea, and acute alcohol poisoning; 8. Pregnant or lactating female patients, or patients with mental disorders; 9. echocardiographic measurement of left atrial anteroposterior diameter >= 50 mm;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Long term success rate post ablation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Short term success rate post ablation;ablation related complications;ablation related parameters;AFEQT and SF-12 Score in 12 months follow up;Biochemical index and echocardiography parameters in; | — |
Countries
China
Contacts
Public ContactQi Jin
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed