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Exploring the efficacy of dexamethasone combined with tachyzoites in preventing severe postoperative infections after PCNL based on SIRS diagnostic criteria: a multicentre randomised controlled trial

Exploring the efficacy of dexamethasone combined with tachyzoites in preventing severe postoperative infections after PCNL based on SIRS diagnostic criteria: a multicentre randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093821
Enrollment
Unknown
Registered
2024-12-12
Start date
2025-01-01
Completion date
Unknown
Last updated
2024-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

kidney stone

Interventions

test group:Dexamethasone 10mg, furosemide 10mg at the start of lithotripsy
control group:saline 20mg at the start of lithotripsy

Sponsors

Changshu Hospital of Traditional Chinese Medicine (Changshu New District Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients whose preoperative urinalysis suggests urinary tract infection, which improves after medication and without fever within three days; 2.Patients who receive one-stage unilateral PCNL surgery; 3.Patients whose age >= 18 years old.

Exclusion criteria

Exclusion criteria: 1. Patients with abnormal preoperative temperature, heart rate, respiration and blood analysis test results that may interfere with the diagnosis of postoperative SIRS; 2. Patients who are allergic to dexamethasone or furosemide; 3.Patients with fever within three days; 4.Patients who cannot cooperate with the clinical trial.

Design outcomes

Primary

MeasureTime frame
Incidence of systemic inflammatory response syndrome three days after surgery;

Secondary

MeasureTime frame
Post-operative ICU admission rate;Length of hospital stay for postoperative patients;hospital fees;

Countries

China

Contacts

Public ContactXu Ke

Changshu Hospital of Traditional Chinese Medicine (Changshu New District Hospital)

1274860890@qq.com+86 512 5234 2750

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026