Postoperative cognitive dysfunction
Conditions
Interventions
Electroacupuncture group:Electroacupuncture stimulation was performed at acupuncture points.
Sham electroacupuncture group:Sham electroacupuncture stimulation was performed at the acupuncture points.
Sponsors
Affiliated Hospital of Nanjing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Elderly patients aged between 65 and 80 years old. 2. In accordance with the American Society of Anesthesiologists classification of grade ?-?. 3. Patients undergoing elective radical gastrectomy under general anesthesia. 4. Preoperative Mini-mental state examination (MMSE) score >=23. 5. Only cefuroxime sodium was used for perioperative antibiotic therapy. 6. Patients who were willing to receive electroacupuncture treatment and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with diseases affecting cognitive function assessment or unable to cooperate with cognitive function assessment. 2. Patients with a history of inflammatory bowel disease and irritable bowel. 3. Patients who had used antibiotics, probiotics, or received other gastrointestinal surgery within 3 months before admission. 4. Patients with a history of severe cardiovascular and cerebrovascular diseases and hepatic and renal insufficiency. 5. Serious adverse reactions or other complications occurred during the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini-mental state examination score;Activity of Daily Living Scale; | — |
Countries
China
Contacts
Public ContactTian Weiqian
Affiliated Hospital of Nanjing University of Chinese Medicine
Outcome results
None listed