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Comparing the Effects of Propofol Combined with Oxazolidine or Fentanyl on Hypoxemia in Non-Intubated Intravenous General Anesthesia Patients

Comparing the Effects of Propofol Combined with Oxazolidine or Fentanyl on Hypoxemia in Non-Intubated Intravenous General Anesthesia Patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400093800
Enrollment
Unknown
Registered
2024-12-12
Start date
2025-02-01
Completion date
Unknown
Last updated
2024-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Depression(Hypoxemia)

Interventions

Group OP(Oliceridine +Propofol):Anesthesia was administered with olceridine and propofol
Group FP(Fentanyl +Propofol):Anesthesia was administered with olcerilidine and propofol

Sponsors

The Third Affiliated Hospital of Sun Yat-sen University,
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients aged 18 to 80 years, ASA physical status I–III, scheduled to undergo non-intubated intravenous general anesthesia (Painless gastroscopy or colonoscopy or hysteroscopy)

Exclusion criteria

Exclusion criteria: Pregnant women, patients with a history of allergy to the study drugs, patients who have used sedatives or analgesics preoperatively, patients who experience cognitive dysfunction during the perioperative period, patients with pre-existing severe systemic diseases such as severe circulatory or respiratory diseases, patients classified as ASA grade 4, patients with difficult airways (such as those with a BMI > 30 kg/m², OSA patients, mouth opening < 4 cm, or Mallampati score = 3), patients with a history of diaphragm surgery, maxillofacial trauma, or surgery, patients with severe anemia or severe peripheral vascular disease, patients with implanted cardiac pacemakers, and patients undergoing therapeutic procedures lasting more than 30 minutes.

Design outcomes

Primary

MeasureTime frame
Incidence of hypoxemia;

Countries

China

Contacts

Public ContactJibin Xing

Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Tianhe District, Guangzhou, China

beenjoy@qq.com+86 135 1272 8239

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026