Patients undergoing total knee arthroplasty under general anesthesia
Conditions
Interventions
Control group:After anesthesia induction,administer lidocaine solution via an intravenous access.
Experimental Group:After anesthesia induction, administer lidocaine solution through the lower limb intravenous access.
Sponsors
The Second Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Obtained the approval and consent of the medical Ethics Committee of the hospital, and signed the informed consent; 2. Aged 18-85 years old; 3. ASA anesthesia grade I-III; 4.Elective total knee arthroplasty under anesthesia was performed.
Exclusion criteria
Exclusion criteria: 1.Lower extremity deep vein thrombosis; 2.Allergy to any medication used in this trial; 3.Pre-existing severe cardiovascular, cerebrovascular, respiratory system diseases, and liver or kidney function abnormalities; 4.History of chronic pain, long-term use of opioids, corticosteroids, or nonsteroidal anti-inflammatory drugs; 5.BMI >= 30 kg/m²; 6.Inability to communicate normally: hearing impairment, language comprehension, mental illness, etc.; 7.Patients enrolled in other trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative morphine consumption after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS scores at rest and during movement after surgery;The first pressing time of postoperative analgesia pump;The first time to get out of bed after operation;Postoperative QoR-15 recovery score;The incidence of postoperative anesthesia-related complications;The first postoperative exhaust time;The number of times rescue analgesia was needed;The incidence of intraoperative tourniquet hypertension (TH).;Quadriceps Manual Muscle Test (MMT) Grading; | — |
Countries
China
Contacts
Public ContactMingjian Kong
The Second Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed