bronchopulmonary dysplasia
Conditions
Interventions
Study Group (Probiotics Group):Clostridium butyricum dual live bacteria powder is injected through gastric tube or taken orally
Control group (non-probiotic group):No probiotics were used.
Sponsors
Henan Provincial People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Premature infants with a gestational age of less than 32 weeks and a birth weight of less than 1500 g. 2. Understand this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those with severe congenital heart and lung malformations and digestive system diseases; 2. Those with inherited metabolic diseases; 3. Parents do not agree to participate in the researcher; 4. Other researchers believe that the clinical trial cannot be completed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence and severity of BPD in children;Incidence of serious complications;Analysis of fecal flora in two groups; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lymphocyte immunoassay results; mechanical ventilation time;oxygen consumption time;hospitalization time;blood routine; liver and kidney function; | — |
Countries
China
Contacts
Public ContactWang Dandan
Henan Provincial People's Hospital
Outcome results
None listed